Find patient medical information for Tadalafil (Cialis, Adcirca, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Cialis is an ED medication you can take once daily or as needed before sexual activity. Learn how to take Cialis and avoid side effects. Cialis is a popular ED medication. Find out everything you need to know about this doctor-prescribed medication including usage, effectiveness, safety considerations, and where to buy online. Cialis is a phosphodiesterase 5 (PDE5) inhibitor for the treatment of erectile dysfunction and benign prostatic hyperplasia. Cialis relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Cialis (tadalafil) is a prescription tablet used for erectile dysfunction and benign prostatic hyperplasia. Learn about dosage, side effects, and more. The maximum recommended dosing frequency is once per day in most patients. CIALIS for use as needed was shown to improve erectile function compared to placebo up to 36 hours following dosing. Therefore, when advising patients on optimal use of CIALIS, this should be taken into consideration.